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Survodutide, a dual GLP-1 and glucagon receptor agonist, produced around 19 percent weight loss in phase 2 trials

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Several centers in the United States and in many other countries recommend treatment only for patients who have a serum concentration that falls above the probable toxicity line, which starts at 200 g per milliliter 4 hours after ingestion

They called on orthopedic surgeons to stay informed, because patients and athletes will continue seeking these treatments regardless of the regulatory landscape